Cloroformiato de etilo
Ethyl chloroformate
CAS: 541-41-3
Molecular Formula: C3H5ClO2
Cloroformiato de etilo - Names and Identifiers
Cloroformiato de etilo - Physico-chemical Properties
| Molecular Formula | C3H5ClO2 |
| Molar Mass | 108.52 |
| Density | 1.135 g/mL at 25 °C (lit.) |
| Melting Point | -81 °C (lit.) |
| Boling Point | 93 °C (lit.) |
| Flash Point | 57°F |
| Water Solubility | decomposes |
| Solubility | Chloroform (Soluble), Ethyl Acetate (Slightly) |
| Vapor Presure | 3.42 psi ( 20 °C) |
| Vapor Density | 3.74 (vs air) |
| Appearance | Liquid |
| Color | White to off-white |
| Odor | Irritating; sharp, like hydrochloric acid. |
| Merck | 14,3784 |
| BRN | 385653 |
| Storage Condition | 2-8°C |
| Stability | Moisture Sensitive |
| Sensitive | Moisture Sensitive |
| Refractive Index | n20/D 1.395(lit.) |
| Physical and Chemical Properties | This product is a colorless liquid, M.P.-81 ℃, B. P. 93 ℃,n20D 1.3950, relative density 1.135,f.p.2 ℃, insoluble in water, soluble in ethanol, ether, benzene and chloroform, this product is toxic and corrosive. |
Cloroformiato de etilo - Risk and Safety
| Risk Codes | R11 - Highly Flammable R22 - Harmful if swallowed R26 - Very Toxic by inhalation R34 - Causes burns R50 - Very Toxic to aquatic organisms |
| Safety Description | S9 - Keep container in a well-ventilated place. S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S33 - Take precautionary measures against static discharges. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 1182 6.1/PG 1 |
| WGK Germany | 1 |
| RTECS | LQ6125000 |
| FLUKA BRAND F CODES | 10-19-21 |
| TSCA | Yes |
| HS Code | 29151300 |
| Hazard Class | 6.1 |
| Packing Group | I |
Cloroformiato de etilo - Nature
Open Data Verified Data
colorless transparent liquid with irritating odor. Flammable, toxic, corrosive. The relative density was 1.1352. Melting Point -81 °c. Boiling point 93 degrees Celsius. Flash point <16 °c. Refractive index 1.3974. It is miscible with ethanol and ether, but can be decomposed by ethanol. Soluble in benzene, chloroform, insoluble in water, and can be decomposed by water.
Last Update：2024-01-02 23:10:35
Cloroformiato de etilo - Preparation Method
Open Data Verified Data
phosgene and anhydrous ethanol esterification reaction to produce ethyl chloroformate, and then through the removal of impurities, dehydration, fractionation and other refining process to obtain the finished product.
Last Update：2022-01-01 10:33:13
Cloroformiato de etilo - Use
Open Data Verified Data
organic synthesis intermediates for the preparation of diethyl formate, isocyanate, pharmaceuticals, pesticides, herbicides and flotation agents.
Last Update：2022-01-01 10:33:12
Cloroformiato de etilo - Safety
Open Data Verified Data
- This product is the same as methyl chloroformate, which is highly toxic. The respiratory tract, eye conjunctiva has a strong stimulating effect. Protection requirements are also the same as for methyl chloroformate. See methyl chloroformate.
- the iron drum is packed with plastic bags. According to the provisions of flammable and toxic hazardous chemicals storage and transportation.
Last Update：2022-01-01 10:33:13
Cloroformiato de etilo - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| traits | ethyl chloroformate is colorless to light yellow transparent liquid. |
| properties | ethyl chloroformate is a colorless and transparent liquid with a pungent smell and a boiling point of 94 ℃. Specific gravity D420:1.1403, soluble in organic solvents such as alcohol and benzene. |
| Uses | Ethyl chloroformate can be used as an intermediate in organic synthesis and can also be used as a solvent. Ethyl chloroformate is an intermediate of the herbicide cyclazinone. Organic synthesis intermediates are used to produce diethyl formate, isocyanate, medicine, pesticides, herbicides and flotation agents. Also used as a solvent. Used as an intermediate in organic synthesis, used to produce urethane, diethyl formate, etc., and also used in medicine, pesticides, and flotation agents. |
| Production method | is obtained by the reaction of ethanol and phosgene. The esterification reaction of phosgene and anhydrous ethanol produces ethyl chloroformate, and then the finished product is obtained by refining processes such as removal of impurities, dehydration, and fractionation. the preparation method is to place anhydrous ethanol in a three-mouth flask, pass phosgene at about 5 ℃, pass in the calculated amount of phosgene, heat to 30 ℃ in a water bath, heat and stir for 30 min, so as to make the reaction more complete. the product is washed with ice water to remove the water layer, and dried to obtain the finished product. CH3CH2OH COCl2→ClCOOC2H5 HCl |
| category | flammable liquid |
| toxicity classification | highly toxic |
| acute toxicity | oral-rat LD50: 270 mg/kg |
| flammability hazard characteristics | flammable in case of open flame, high temperature and oxidant; Combustion produces toxic chloride smoke; High heat decomposes toxic phosgene; Corrosive gas produced in contact with water |
| storage and transportation characteristics | warehouse ventilation and low temperature drying; separate from oxidant |
| fire extinguishing agent | dry powder, dry sand, carbon dioxide, foam, 1211 fire extinguishing agent |
| occupational standard | TWA 4.4 mg/m3 |
| auto-ignition temperature | 842 °F |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 02:00:09
